Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression
Identifieur interne : 001680 ( Main/Exploration ); précédent : 001679; suivant : 001681Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression
Auteurs : Krishna Narayanan [États-Unis] ; Sydney I. Ramirez [États-Unis] ; Kumari G. Lokugamage [États-Unis] ; Shinji Makino [États-Unis]Source :
- Virus Research [ 0168-1702 ] ; 2014.
Descripteurs français
- KwdFr :
- Animaux, Coronavirus (croissance et développement), Coronavirus (pathogénicité), Coronavirus (physiologie), Facteurs de virulence (métabolisme), Humains, Interactions hôte-pathogène, Mammifères, Protéines virales non structurales (métabolisme), Régulation de l'expression des gènes, Régulation de l'expression des gènes viraux, Virulence.
- MESH :
- croissance et développement : Coronavirus.
- métabolisme : Facteurs de virulence, Protéines virales non structurales.
- pathogénicité : Coronavirus.
- physiologie : Coronavirus.
- Animaux, Humains, Interactions hôte-pathogène, Mammifères, Régulation de l'expression des gènes, Régulation de l'expression des gènes viraux, Virulence.
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Viral Nonstructural Proteins, Virulence Factors.
- growth & development : Coronavirus.
- pathogenicity : Coronavirus.
- physiology : Coronavirus.
- Animals, Gene Expression Regulation, Gene Expression Regulation, Viral, Host-Pathogen Interactions, Humans, Mammals, Virulence.
Abstract
Novel strategies to inhibit host gene expression by coronavirus nonstructural protein 1. Summarizes the conserved and divergent functions of Alpha and Betacoronavirus nsp1. Provides a mechanistic insight into the unique properties of SARS coronavirus nsp1.
Url:
DOI: 10.1016/j.virusres.2014.11.019
PubMed: 25432065
PubMed Central: 4444399
Affiliations:
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Le document en format XML
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Ramirez</name><affiliation wicri:level="2"><nlm:aff id="aff0010">Department of Pathology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555-1019, United States</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555-1019</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Lokugamage, Kumari G" sort="Lokugamage, Kumari G" uniqKey="Lokugamage K" first="Kumari G." last="Lokugamage">Kumari G. Lokugamage</name><affiliation wicri:level="2"><nlm:aff id="aff0005">Department of Microbiology and Immunology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555-1019, United States</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology and Immunology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555-1019</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Makino, Shinji" sort="Makino, Shinji" uniqKey="Makino S" first="Shinji" last="Makino">Shinji Makino</name><affiliation wicri:level="2"><nlm:aff id="aff0005">Department of Microbiology and Immunology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555-1019, United States</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology and Immunology, The University of Texas Medical Branch at Galveston, Galveston, TX 77555-1019</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author></analytic><series><title level="j">Virus Research</title><idno type="ISSN">0168-1702</idno><idno type="eISSN">1872-7492</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Coronavirus (growth & development)</term><term>Coronavirus (pathogenicity)</term><term>Coronavirus (physiology)</term><term>Gene Expression Regulation</term><term>Gene Expression Regulation, Viral</term><term>Host-Pathogen Interactions</term><term>Humans</term><term>Mammals</term><term>Viral Nonstructural Proteins (metabolism)</term><term>Virulence</term><term>Virulence Factors (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Coronavirus (croissance et développement)</term><term>Coronavirus (pathogénicité)</term><term>Coronavirus (physiologie)</term><term>Facteurs de virulence (métabolisme)</term><term>Humains</term><term>Interactions hôte-pathogène</term><term>Mammifères</term><term>Protéines virales non structurales (métabolisme)</term><term>Régulation de l'expression des gènes</term><term>Régulation de l'expression des gènes viraux</term><term>Virulence</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Viral Nonstructural Proteins</term><term>Virulence Factors</term></keywords><keywords scheme="MESH" qualifier="croissance et développement" xml:lang="fr"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Facteurs de virulence</term><term>Protéines virales non structurales</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Gene Expression Regulation</term><term>Gene Expression Regulation, Viral</term><term>Host-Pathogen Interactions</term><term>Humans</term><term>Mammals</term><term>Virulence</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Humains</term><term>Interactions hôte-pathogène</term><term>Mammifères</term><term>Régulation de l'expression des gènes</term><term>Régulation de l'expression des gènes viraux</term><term>Virulence</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Highlights</title><p><list list-type="simple" id="lis0005"><list-item id="lsti0005"><label>•</label><p id="par0005">Novel strategies to inhibit host gene expression by coronavirus nonstructural protein 1.</p></list-item><list-item id="lsti0010"><label>•</label><p id="par0010">Summarizes the conserved and divergent functions of Alpha and Betacoronavirus nsp1.</p></list-item><list-item id="lsti0015"><label>•</label><p id="par0015">Provides a mechanistic insight into the unique properties of SARS coronavirus nsp1.</p></list-item></list></p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Almeida, M S" uniqKey="Almeida M">M.S. 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Kuri</name></author><author><name sortKey="Blakqori, G" uniqKey="Blakqori G">G. Blakqori</name></author><author><name sortKey="Weber, F" uniqKey="Weber F">F. Weber</name></author><author><name sortKey="Ludewig, B" uniqKey="Ludewig B">B. Ludewig</name></author><author><name sortKey="Thiel, V" uniqKey="Thiel V">V. Thiel</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Texas</li></region></list><tree><country name="États-Unis"><region name="Texas"><name sortKey="Narayanan, Krishna" sort="Narayanan, Krishna" uniqKey="Narayanan K" first="Krishna" last="Narayanan">Krishna Narayanan</name></region><name sortKey="Lokugamage, Kumari G" sort="Lokugamage, Kumari G" uniqKey="Lokugamage K" first="Kumari G." last="Lokugamage">Kumari G. Lokugamage</name><name sortKey="Makino, Shinji" sort="Makino, Shinji" uniqKey="Makino S" first="Shinji" last="Makino">Shinji Makino</name><name sortKey="Ramirez, Sydney I" sort="Ramirez, Sydney I" uniqKey="Ramirez S" first="Sydney I." last="Ramirez">Sydney I. Ramirez</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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